OK! Despite my jaundiced view of the safety of the system (especially as operated by a NASA hierarchy that I don't believe is CAPABLE of changing itself where shuttle ops is concerned) I'm paradoxically quivering with Go Fever as badly as anybody. There is still hardware I touched in those SSMEs and I'll sweat ascent like I always do, especially that first 120 seconds - as I've said elsewhere, I really hate those damned SRBs! I have huge confidence in the SSMEs. (A bit prejudiced, I know, but they aren't going to fail with no warning!!)
We're flying an aging, hideously complex system whose operational lifetime per orbiter was originally specified as 10 years or 100 flights. Just because flight rates are low doesn't mean that things like wiring aren't degraded from environmental factors. Even Endeavour is 13 years past her first flight and exceeding design operational age. I fervently hope that we can keep slapping adequate fixes on problems as they are found - but I dread the reality that could slap us in the face at any time - a fatal accident from a previously unforeseen and unhinted-at fault that doesn't reveal itself in minor glitches first.